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China factory - Orient New Life Medical Co.,Ltd.

Orient New Life Medical Co.,Ltd.

  • China,Ningbo ,Zhejiang
  • Verified Supplier

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China Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein
China Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein

  1. China Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein
  2. China Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein
  3. China Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein

Recombinant 2019-NCoV Mouse Monoclonal Antibody Spike RBD Protein

  1. MOQ: 1mg
  2. Price: USD
  3. Get Latest Price
Payment Terms T/T, Western Union, MoneyGram
Supply Ability 1108mg/month
Delivery Time 10-35days
Packaging Details 0.5mg/tube 1mg/tube, 2mg/tube、5mg/tube、10mg/tube、20mg/tube、30mg/tube
Category mAb mouse Mono
Application COVID 19 Neutralization
Usage ELISA,wb
Specimen Blood,
Shelf Life 18 months
Concerntraion 1mg
Brand Name New Life
Model Number 40592-MM57
Certification ISO13485
Place of Origin China

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  1. Product Details
  2. Company Details

Product Specification

Payment Terms T/T, Western Union, MoneyGram Supply Ability 1108mg/month
Delivery Time 10-35days Packaging Details 0.5mg/tube 1mg/tube, 2mg/tube、5mg/tube、10mg/tube、20mg/tube、30mg/tube
Category mAb mouse Mono Application COVID 19 Neutralization
Usage ELISA,wb Specimen Blood,
Shelf Life 18 months Concerntraion 1mg
Brand Name New Life Model Number 40592-MM57
Certification ISO13485 Place of Origin China
High Light RBD Protein Mouse Monoclonal AntibodyCOVID 19 Neutralization Mouse Monoclonal Antibody

 

 

 

Recombinant 2019-nCoV Mouse Monoclonal Antibody Spike RBD Protein

 

Background

 

The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cellsobtained from a mouse immunized with purified, Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD-mFc Protein. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

 

Name

2019-nCoV Mouse Monoclonal Antibody Spike RBD Protein

 

Application Invitro research and manufacture use;
membrane assay, ELISA assay,
Perseverative

1 0.02% sodium azide.

 

Buffer: 1X PBS buffer
Storage: Short-term: refrigerated at 2-8 ºC; long term: frozen at or
below -20 ºC.
Concentration 1.0 mg/mL
Expiration Date: 14 days refrigerated at -2-8ºC
and two years frozen at -20 ºC
or below from production date.
To be evaluated independently
Feature High Sensitivity and Specificity

 

 

Specification Data

 

 

Description: Monoclonal Antibody to Acetaminophene
Clone: SARS-CoV-2 (2019-nCoV) Spike RBD Protein  
Source: Mouse IgG2b  
Immunogen:

 

SARS-CoV-2 (2019-nCoV) Spike S1 Protein

 
Formulation:

 

0.2 μm filtered solution in PBS

 
Purification: DEAE chromatography  
Concentration: 1.0 mg/mL (OD280 nm, E0.1% = 1.40)
Affinity Constant: Not determined  
Buffer: 0.015M potassium phosphate buffer, 0.85% NaCl, 0.05% NaN3 pH=7.2
Pairing Assays: N/A  
Purity: >90% by HPLC and SDS-PAGE
Application:

 

Neutralization, ELISA

Storage: 2-8o C for 1 year. Store at -200 C for long term.

 

The neutralization activity is Measured by microneutralization assay in vitro. The virus microneutralizaiton (MN) test was performed on 293T-ACE2 cells infected with SARS-CoV-2 (2019-nCoV) Spike Pseudovirus under treatment of serial dilutions of neutralizing antibody. The infection was neutralized by increasing concentrations of Anti-SARS-CoV-2 Neutralizing Antibody (Catalog# 40592-MM57). Rate of inhibition was determined by comparing the Relative Light Unit (RLU) of Luciferase reporter in different antibody concentrations. The IC50 is typically 0.41 µg/mL.

 

Loaded SARS-CoV-2 (2019-nCoV) Spike RBD-His Recombinant Protein,Biotinylated on SA Biosensor, can bind SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody, Mouse MAb with an affinity constant of 0.07 nM as determined by Octet RED System.

 

Loaded SARS-CoV-2 (2019-nCoV) Spike S1-His Recombinant Protein,Biotinylated on SA Biosensor, can bind SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody, Mouse MAb with an affinity constant of 0.05 nM as determined by Octet RED System

 

FAQ

1. Q:Are you a factory or trading company?
A: We are a factory, we have rich experience for manufacturing Medical Device more than 10 years.
2.Q:Where is your factory located? How can i visit there?
A: Our factory is located in Jiaxing city, Zhejiang Province, China.
It is about more than 1 hours from Shanghai.

2. 3.Q:Can you make samples?
A: Yes, we can make samples for you.
4.Q:How does your factory do as quality control?
A: Quality is the lift of our factory. We have inspector in different post, and there are three inspectors before packing to get best quality products.
5.Q: How is your post market service ?
A: If any damaged rings in the course of carriage, with the checking it's our mistake, we will take full responsibility to compensate the customers.

6.Q:Can you do OEM for us?
A: Certainly. We also can build the moulding for our new customer.

7.Q:Does the price include freight?
A:No, please choose the express service provider or negotiate with us.

 

Company Details

Bronze Gleitlager

,

Bronze Sleeve Bushings

 and 

Graphite Plugged Bushings

 from Quality China Factory
  • Business Type:

    Manufacturer,Exporter

  • Year Established:

    2009

  • Total Annual:

    10,000,000-15,000,000

  • Employee Number:

    200~300

  • Ecer Certification:

    Verified Supplier

Established in 2009, Orient New Life Medical Co., Ltd., is specialized in high-tech biological diagnostic test development, research and production, as well as high-tech medical device development, research and production. New Life has built up two production base, which produce biological diagnosti... Established in 2009, Orient New Life Medical Co., Ltd., is specialized in high-tech biological diagnostic test development, research and production, as well as high-tech medical device development, research and production. New Life has built up two production base, which produce biological diagnosti...

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Get in touch with us

  • Reach Us
  • Orient New Life Medical Co.,Ltd.
  • 12F,Guting Building,Hefeng Creative Square,No.495 Jiangdong North Road,Ningbo,Zhejiang, China
  • MrJerry Meng
  • +86-18657312116

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