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Lithium Heparin is a high-purity anticoagulant agent widely used in clinical laboratories and medical settings, specifically designed to prevent blood sample clotting while preserving the integrity of blood components. It works by binding to antithrombin III, accelerating the inhibition of thrombin and factor Xa—key enzymes in the blood coagulation cascade—thus maintaining the sample in a liquid state for accurate testing. Available in multiple forms (e.g., lyophilized powder, pre-coated in blood collection tubes, or solution for manual addition), it is compatible with most hematology, clinical chemistry, and immunology analyzers. Manufactured under strict GMP standards, it meets ISO and CE medical grade requirements, ensuring low impurity levels (e.g., minimal sodium or potassium residues) to avoid interfering with test results, especially electrolyte analyses.
Key Features
Efficient Anticoagulation:Rapidly inhibits blood clotting within 1-2 minutes of contact, maintaining sample stability for up to 4-8 hours at room temperature (or 24+ hours under refrigeration).
Minimal Test Interference:Low ion content (especially lithium) reduces cross-reactivity with electrolyte tests (e.g., sodium, potassium) and avoids affecting glucose, urea, or enzyme activity measurements.
Versatile Forms:Offered as lyophilized powder (easy storage, long shelf life), pre-coated tubes (ready-to-use, saves lab time), or sterile solution (flexible for custom sample volumes).
High Purity & Safety:Purified to remove endotoxins and contaminants; biocompatible formula prevents hemolysis (red blood cell damage) and ensures sample quality.
Broad Compatibility:Suitable for both serum and plasma separation (when used with appropriate tubes) and works with automated laboratory equipment for high-throughput testing.
Application Scenarios
Clinical Chemistry Testing:Ideal for analyzing electrolytes (sodium, potassium, chloride), glucose, cholesterol, triglycerides, and liver/kidney function markers (e.g., ALT, creatinine).
Hematology & Immunology:Used for complete blood count (CBC) screening, cytokine detection, and autoimmune antibody tests (where unclotted plasma is required).
Emergency & Point-of-Care Testing:Fast-acting anticoagulation supports rapid sample processing in emergency departments or on-site clinics (e.g., blood gas analysis, urgent electrolyte checks).
Research Settings:Applied in academic or pharmaceutical research for studying blood coagulation mechanisms, developing anticoagulant drugs, or preserving blood samples for cell culture.
In Summary:
The primary and indispensable function of Lithium Heparin is to effectively prevent blood clotting in collection tubes by enhancing antithrombin activity, thereby enabling the reliable collection of plasma samples. Its key advantage lies in the use of lithium as the counter-ion, which minimizes interference with a broad spectrum of routine clinical chemistry analytes, particularly electrolytes, making it the workhorse anticoagulant for general biochemistry testing in modern clinical laboratories.
Shanghai Orsin Medical Technology Co., Ltd. is located in No. 599, Wanhua Road, Zhelin Town, Fengxian District, Shanghai. Is China's production of one-time vacuum collection of professional companies, Shanghai Medical Device Industry Backbone Enterprises. The product takes Orsin pattern as the r... Shanghai Orsin Medical Technology Co., Ltd. is located in No. 599, Wanhua Road, Zhelin Town, Fengxian District, Shanghai. Is China's production of one-time vacuum collection of professional companies, Shanghai Medical Device Industry Backbone Enterprises. The product takes Orsin pattern as the r...