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- GMP factory supply high purity KPV peptide CAS 67727-97-3 KPV powder
- Product Details
- Company Details
Product Specification
|
|
|
|
| Payment Terms |
L/C,D/A,D/P,T/T,Western Union |
Specification |
1g/5g/bag |
| Color |
white |
Type |
Glp-2 |
| Test Method |
HPLC HNMR |
Einecs |
67727-97-3 |
| Casnumber |
Varies by peptide |
Packagingmaterial |
PVC bottle or aluminium foil bag |
| Stocks |
Yes |
Appearence |
Powder |
| Storage Temp |
2-8°C |
Supply Ability |
5kg/month |
| Delivery Time |
3-7 days |
Lead Time |
3-5 working days after payment |
| Puritylevel |
Pharmaceutical grade |
Product Type |
Custom Peptide |
| Packaging Details |
PVC bottle or aluminium foil bag |
Certification |
DMF |
| Brand Name |
Bovita |
Model Number |
BVR06 |
| Place of Origin |
Wuhan |
| |
| High Light |
GMP factory KPV peptide powder
，high purity KPV peptide
，KPV peptide powder research
|
KPV (CAS 67727-97-3) Product Details
Product Name: KPV
Synonyms: Lys-Pro-Val, KPV Tripeptide, L-Lysyl-L-prolyl-L-valine, Lysyl-Prolyl-Valine
CAS Number: 67727-97-3
Molecular Formula: C₁₄H₂₅N₃O₄
Molecular Weight: 299.37 g/mol
Purity: ≥98% (HPLC)
Grade: Research Grade / Laboratory Grade
1. Product Overview
KPV is a naturally occurring tripeptide composed of three essential amino acids: L-lysine, L-proline, and L-valine. As an active fragment of α-melanocyte-stimulating hormone (α-MSH), it possesses significant biological activities, including anti-inflammatory, antioxidant, and melanocyte-regulating properties. This peptide is widely recognized as a valuable tool in biochemical research, pharmaceutical R&D, and dermatological research, particularly in studies related to skin disorders such as vitiligo.
Our KPV is synthesized using advanced solid-phase peptide synthesis technology, ensuring high purity, excellent stability, and consistent batch-to-batch performance. It is manufactured under strict quality control standards, making it suitable for a wide range of laboratory and research applications.
2. Physical & Chemical Properties
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Appearance: White to off-white crystalline powder
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Solubility: Soluble in water, methanol, and DMSO; slightly soluble in ethanol
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Melting Point: 185–190°C (decomposition)
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Loss on Drying: ≤2.0%
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Heavy Metals: ≤10 ppm
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Endotoxin: <0.5 EU/mg
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Optical Rotation: [α]²⁰/D = -25° to -30° (c=1, H₂O)
3. Key Specifications
|
Test Item
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Standard Specification
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Assay (HPLC)
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≥98.0%
|
|
Appearance
|
White to off-white crystalline powder
|
|
Loss on Drying
|
≤2.0%
|
|
Heavy Metals
|
≤10 ppm
|
|
Endotoxin
|
<0.5 EU/mg
|
|
Melting Point
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185–190°C (dec.)
|
|
Optical Rotation
|
[α]²⁰/D = -25° to -30° (c=1, H₂O)
|
4. Applications & Uses
KPV is widely used in biochemical research, pharmaceutical R&D, and dermatological studies, primarily for its unique biological activities. Key applications include:
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Dermatological Research: Applied in vitiligo research, as it can promote melanocyte proliferation, enhance melanin synthesis, and protect melanocytes from oxidative stress, supporting skin repigmentation studies. It is also used in anti-aging and skin repair research due to its anti-inflammatory properties.
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Biochemical & Pharmacological Research: Used to study the biological functions of α-MSH fragments, including their role in immune regulation, anti-inflammatory responses, and antioxidant defense mechanisms.
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Pharmaceutical R&D: Serves as a lead compound in the development of drugs for skin disorders, anti-inflammatory agents, and antioxidants.
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Laboratory Applications: Used in peptide structure-function studies, cell culture experiments, and enzyme activity assays related to melanocyte regulation and inflammation.
Note: For RESEARCH ONLY / LABORATORY USE ONLY. Not for human, veterinary, or clinical diagnostic use.
5. Mechanism of Action
As an active fragment of α-MSH, KPV exerts its biological effects through multiple mechanisms:
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It binds to melanocortin receptors (MCRs) on melanocytes, activating signaling pathways that promote melanocyte proliferation and melanin synthesis, which is crucial for skin repigmentation in vitiligo research.
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It exhibits potent anti-inflammatory activity by inhibiting the production of pro-inflammatory cytokines and reducing oxidative stress, thereby protecting cells from inflammation-induced damage.
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It enhances the antioxidant capacity of cells, scavenging reactive oxygen species (ROS) and improving the survival microenvironment of melanocytes, which is beneficial for the treatment of oxidative stress-related skin disorders.
6. Storage & Handling
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Storage Conditions:
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Powder: Store at -20°C for 2 years; 4°C for 1 year (sealed, protected from moisture and light).
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Solution: Store at -80°C for long-term storage; avoid repeated freeze-thaw cycles (recommend preparing fresh solutions when needed).
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Handling Precautions: Wear lab coat, nitrile gloves, and safety goggles when handling. Avoid inhalation of dust and contact with skin/eyes. Wash hands thoroughly after use.
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Incompatibility: Avoid contact with strong oxidizing agents and acidic/basic solutions.
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Waste Disposal: Dispose of unused product and waste according to local chemical waste regulations.
7. Packaging & Shipping
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Packaging Options:
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Small Pack: 1mg, 5mg, 10mg, 50mg, 100mg (sealed foil bag or amber glass vial, moisture-proof).
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Bulk Pack: 1g, 5g, 10g, 50g (fiber drum with PE liner, sealed to preserve peptide activity).
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Shipping Information:
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Non-hazardous for air and ground transport.
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Shipping Method: Worldwide express (DHL, FedEx, UPS) for fast delivery (3-7 business days).
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Temperature Control: Shipped with ambient temperature or ice pack; avoid extreme heat or freezing.
8. Quality Assurance & Documentation
We adhere to strict quality control standards to ensure the purity and stability of our KPV. All batches are tested by HPLC, NMR, and MS, and we provide the following documents upon request:
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Certificate of Analysis (COA) with full test results
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Material Safety Data Sheet (MSDS)
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Technical Data Sheet (TDS)
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Stability data and solubility guidelines
Our production facility is ISO-certified, ensuring consistent quality and reliable supply.
9. Why Choose Our KPV?
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High Purity: ≥98% HPLC purity, suitable for sensitive research and assays.
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Advanced Synthesis: Manufactured using solid-phase peptide synthesis technology for high purity and structural integrity.
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Consistent Quality: Strict batch-to-batch control ensures reliable performance in research applications.
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Secure Packaging: Moisture-proof, light-resistant packaging to preserve peptide activity and stability.
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Global Service: Fast worldwide shipping, professional technical support, and custom packaging options.
Contact Us
For bulk pricing, COA samples, custom specifications, or technical inquiries, please contact us directly.
We supply research institutes, biotech companies, and pharmaceutical labs worldwide,
and we are committed to providing high-quality products and professional service.
Company Details
Bronze Gleitlager
,
Bronze Sleeve Bushings
and
Graphite Plugged Bushings
from Quality China Factory
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Business Type:
Manufacturer,Distributor/Wholesaler,Exporter
-
-
Total Annual:
5000000-6000000
-
Employee Number:
50~100
-
Ecer Certification：
Verified Supplier
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