Shijiazhuang Zhongzheng Technology Co., Ltd.
| Material | Stainless Steel, Carbon Steel |
| Supply Ability | 200 sets / days |
| Applications | Chemical, Food Processing, Beverage Processing, Brewing, Metallurgy, Oil Refining, Pharmaceuticals |
| Payment Terms | L/C,T/T |
| Delivery Time | 2 months |
| Design Pressure | 0.1-10 Mpa |
| Size | Customized |
| Place of Origin | China |
| Certification | ASME,ISO 9001,CE, NSF/ANSI 61, WRAS, ISO 28765, LFGB, BSCI, ISO 45001 |
| Brand Name | Center Enamel |
View Detail Information
Explore similar products
Advantages of Shell and Tube Heat Exchangers: A Technical Analysis
Stainless Steel Oil Cooler Heat Exchanger with Customized Size and 0.1-10 Mpa
Industrial Transfer Heat Exchanger with Advanced Thermal Solutions and
Stainless Steel Oil Cooler with Customized Size and 0.1-10 Mpa Design Pressure
Product Specification
| Material | Stainless Steel, Carbon Steel | Supply Ability | 200 sets / days |
| Applications | Chemical, Food Processing, Beverage Processing, Brewing, Metallurgy, Oil Refining, Pharmaceuticals | Payment Terms | L/C,T/T |
| Delivery Time | 2 months | Design Pressure | 0.1-10 Mpa |
| Size | Customized | Place of Origin | China |
| Certification | ASME,ISO 9001,CE, NSF/ANSI 61, WRAS, ISO 28765, LFGB, BSCI, ISO 45001 | Brand Name | Center Enamel |
| High Light | fermenter reactor design ，fermenter reactor principles ，fermenter reactor applications | ||
What Is a Fermenter Reactor? Design, Principles & Applications
Answering the core question: What is a fermenter reactor, and how does it grow microorganisms into valuable biochemicals? A fermenter reactor is a sterile, aerated vessel that cultivates bacteria, yeast, or mammalian cells under controlled temperature (30-37 degree C), pH (5-7.5), and dissolved oxygen (DO above 30 percent saturation). Mechanical agitation at 50-200 rpm with sparged air delivers a volumetric mass-transfer coefficient kLa of 50-400 per hour, sustaining cell densities above 10^9 CFU/mL. Industrial units range from 0.5 m3 pilot tanks to 300 m3 production fermenters, producing antibiotics, enzymes, beer, and bioethanol at yields of 80-95 percent substrate conversion.
Core Operating Principles of Fermenter Reactors
Major Types of Fermenter Reactors
Fermenter Reactor Types Comparison Matrix
| Fermenter Type | Agitation | Scale Range | Typical kLa / DO |
|---|---|---|---|
| Stirred-Tank | Mechanical Rushton/HE-3 | 0.5-300 m3 | kLa 100-400/h, DO>30% |
| Air-Lift | Pneumatic (no shaft) | 1-200 m3 | kLa 50-150/h, low shear |
| Hollow-Fiber | Perfusion, membrane | 0.01-10 m3 | High cell density, gentle |
| Fixed-Bed | Trickle / packed | 0.1-50 m3 | Immobilized cells |
Frequently Asked Questions (FAQ)
Q: What is kLa and why is it critical?
A: kLa is the volumetric mass-transfer coefficient describing how fast oxygen enters the liquid; insufficient kLa starves cells, cutting growth rate mu and product titer.
Q: How is a fermenter kept sterile?
A: SIP steam sterilizes the vessel and lines at 121-134 degree C, while 0.2 micrometer hydrophobic or HEPA filters sterilize incoming air and trap exhaust, preventing contamination.
Q: What is fed-batch fermentation?
A: Nutrient is added gradually instead of all at once, avoiding high substrate concentrations that inhibit cells and raising final yield to 80-95 percent.
Q: Which fermenter best suits shear-sensitive cells?
A: Air-lift and hollow-fiber bioreactors provide low-shear, bubble-driven or membrane-based mixing ideal for mammalian and plant cells.
Company Details
Business Type:
Manufacturer
Year Established:
2008
Total Annual:
100,000,000-200,000,000
Employee Number:
400~500
Ecer Certification：
Verified Supplier
Shijiazhuang Zhengzhong Technology Co., Ltd (Center Enamel) is a leading high-tech enterprise specializing in the research, development, manufacturing, and sales of a diverse range of equipment. Our core business revolves around providing top-tier solutions, including Glass-Fused-to-Steel (GFS) tank... Shijiazhuang Zhengzhong Technology Co., Ltd (Center Enamel) is a leading high-tech enterprise specializing in the research, development, manufacturing, and sales of a diverse range of equipment. Our core business revolves around providing top-tier solutions, including Glass-Fused-to-Steel (GFS) tank...
Get in touch with us
Leave a Message, we will call you back quickly!