CHPS Pharmaceutical Intermediate – White Crystalline Organic Sulfonate for

Product Specification

Product Description:

Sodium 3-Chloro-2-hydroxypropanesulfonate (abbreviated as CHPS) is an important pharmaceutical intermediate and specialty chemical used extensively in the synthesis of surfactants, pharmaceuticals, and various organic compounds. It appears as a white crystalline powder with excellent chemical stability and high purity, making it a reliable raw material for industrial applications requiring precision and consistency.

The chemical structure of CHPS includes a three-carbon backbone with functional groups such as a hydroxyl group (-OH), a chlorine atom (-Cl), and a sulfonate group (-SO3Na). This unique combination of functional groups imparts the compound with excellent reactivity and versatility, allowing it to participate in diverse chemical reactions including nucleophilic substitution, sulfonation, and polymerization processes.

In the production of surfactants, CHPS serves as a key intermediate to introduce hydrophilic sulfonate groups, improving the surface activity and biodegradability of the final products. Surfactants derived from CHPS are widely used in detergents, personal care products, and industrial cleaning agents due to their excellent foaming, emulsifying, and dispersing properties. Moreover, the biodegradability of these surfactants aligns with growing environmental regulations and consumer demand for eco-friendly products.

Beyond surfactants, CHPS is also employed as a building block in pharmaceutical synthesis. Its hydroxyl and chlorine functional groups offer multiple reactive sites for further chemical modification, facilitating the creation of various drug intermediates and active pharmaceutical ingredients (APIs). The presence of the sulfonate group enhances the compound’s solubility in aqueous media, which is critical in many pharmaceutical processes.

CHPS exhibits excellent water solubility and is stable under normal storage conditions, allowing for easy handling and incorporation into aqueous formulations. Its purity is typically guaranteed to be above 98%, ensuring minimal impurities that might otherwise interfere with downstream applications.

The compound’s moisture content is carefully controlled to below 1.0% to maintain its crystalline integrity and prevent degradation. The pH value of a 1% aqueous solution ranges from 6.0 to 8.0, indicating its mild neutrality which is compatible with various chemical environments.

Due to its multifunctional nature, CHPS finds applications in custom chemical synthesis, where it can be tailored for specific processes and formulations. It is also considered a valuable intermediate in specialty chemicals manufacturing, including dye and pigment production, polymer additives, and corrosion inhibitors.

When handling CHPS, it is important to store the material in a cool, dry place away from direct sunlight and incompatible substances such as strong oxidizers and acids. Proper packaging ensures the maintenance of product quality during transportation and storage.

In summary, Sodium 3-Chloro-2-hydroxypropanesulfonate (CHPS) is a versatile and high-purity chemical intermediate essential for modern surfactant production, pharmaceutical synthesis, and specialty chemical manufacturing. Its well-balanced physical and chemical properties enable it to meet stringent industrial requirements and support sustainable product development.

Technical Specifications:

Typical Applications:

Sodium 3-Chloro-2-hydroxypropanesulfonate is predominantly used as an intermediate in the production of biodegradable surfactants, which are essential in household and industrial cleaning products. The surfactants synthesized from CHPS exhibit superior foaming capacity, excellent emulsification, and strong detergency. They also demonstrate good skin compatibility, making them suitable for personal care formulations such as shampoos, body washes, and liquid soaps.

In pharmaceutical manufacturing, CHPS functions as a reactive intermediate enabling the synthesis of various drug compounds. The compound’s hydroxyl and chlorine groups provide sites for substitution and addition reactions, facilitating the construction of complex molecular structures needed in APIs. Additionally, the sulfonate group enhances water solubility and bioavailability of certain pharmaceutical products.

The specialty chemicals sector benefits from CHPS as a precursor in the formulation of dye intermediates, polymer additives, and corrosion inhibitors. Its functional groups enable chemical modifications that improve the performance and durability of end-use products. For instance, CHPS-derived additives can enhance polymer flexibility and resistance to environmental degradation.

Furthermore, CHPS can be utilized in water treatment chemicals as a component of formulations aimed at reducing scale and corrosion. Its sulfonate group contributes to chelation properties that bind metal ions, improving the effectiveness of water conditioning agents.