Hoyoshee Chemical industrial Co.Ltd
| Payment Terms | L/C,D/A,D/P,T/T,Western Union,MoneyGram |
| Supply Ability | 200 Ton/Month |
| Delivery Time | ONE WEEK |
| Packaging Details | plastic drums or IBC totes |
| Brand Name | HOYOSHEE |
| Model Number | HYX-793 |
| Certification | ISO9001 |
| Place of Origin | China |
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Product Specification
| Payment Terms | L/C,D/A,D/P,T/T,Western Union,MoneyGram | Supply Ability | 200 Ton/Month |
| Delivery Time | ONE WEEK | Packaging Details | plastic drums or IBC totes |
| Brand Name | HOYOSHEE | Model Number | HYX-793 |
| Certification | ISO9001 | Place of Origin | China |
| High Light | Creatinol-O-Phosphate CAS 6903-79-3 ，CAS 6903-79-3 Phospholipid Compound ，Creatinol-O-Phosphate Powder crystals | ||
| chemical name | Creatinol-O-Phosphate |
|---|---|
| CAS Number | 6903-79-3 |
| EINECS No. | 230-001-8 |
| English Synonyms | 1-(2-hydroxyethyl)-1-methylguanidinedihydrogenphosphate; CREATINOLFOSFATE; creatinolphosphate; 2-[carbamimidoyl(methyl)amino]ethyldihydrogenphosphate; CREATINOLO-PHOSPHATE; CREATINOLO-PHOSPHATEANDITSSODIUMSALT; 1-[2-(Phosphonooxy)ethyl]-1-methylguanidine; Aplodan |
COP continues to be used in biochemical research and as a reference standard. It has been investigated for potential applications in:
Cardiovascular health (ischemic heart disease, arrhythmias)
Rheumatoid arthritis and other inflammatory conditions (under investigation)
Diabetic retinopathy (under investigation)
In the supplement industry, COP is marketed as an ergogenic aid for athletes and individuals engaged in intense physical training. Purported benefits include:
Enhanced muscle endurance and contractility
Delayed onset of muscle fatigue
Improved recovery post-exercise
Reduced muscle damage during high-intensity workouts
These claims are based primarily on theoretical mechanisms and older injection studies, not on modern oral supplementation trials.
Recent research has identified novel applications for COP. A 2024 study demonstrated its use as an interface modification material in perovskite solar cells, where it passivated surface defects and improved power conversion efficiency to 24.45%, also enhancing device stability. This highlights the compound's potential in materials science beyond biomedical applications.
As there are no established guidelines for oral supplementation, typical recommendations are based on anecdotal sources and historical injection data:
| Context | Typical Dosage |
|---|---|
| Supplement (oral) | 1–3 grams daily, often taken before workouts |
| Strength training | ~2 grams daily for endurance benefits |
| Clinical (IV, historical) | Up to 3 grams daily under medical supervision |
Note: Due to the lack of oral bioavailability data, these dosages are not evidence-based. Anyone considering COP supplementation should consult a healthcare professional.
Mild: Gastrointestinal discomfort (with excessive oral doses)
Rare: Dizziness or headaches
With IV administration (historical): No significant toxicity observed at doses up to 3g; some reports noted increased urinary phosphorus and mild diuresis
Pregnancy and Nursing: No safety data available; avoid use.
Heart Conditions: Individuals with heart conditions should consult a healthcare provider before use.
Regulatory Status:
United States: Legal as a dietary supplement ingredient.
European Union: Permitted within safety regulations.
Canada: Permitted under natural health product guidelines.
No long-term safety studies are available.
No modern clinical trials have evaluated oral COP.
The compound is considered a research chemical and should not be used for therapeutic purposes without professional guidance.
| Property | Creatinol-O-Phosphate (COP) | Creatine Monohydrate |
|---|---|---|
| CAS Number | 6903-79-3 | 6020-87-7 |
| Molecular Formula | C₄H₁₂N₃O₄P | C₄H₉N₃O₂ |
| Origin | Synthetic | Naturally occurring |
| Primary Use | Cardioprotective, sports supplement | Muscle energy, strength gains |
| Evidence Base | Limited to old IV studies; no oral data | Extensive research on oral use |
| Metabolism | Converts to creatinol (not creatine) | Converts to phosphocreatine |
For practical purposes, COP should be viewed as a completely different molecule from creatine, with no proven equivalence in effect
Company Details
Business Type:
Manufacturer
Year Established:
2010
Total Annual:
3000W-0.2B
Employee Number:
100~500
Ecer Certification：
Verified Supplier
Hunan Hoyoshee Chemical Industrial Co.Ltd was established in 2019, it is a high-tech enterprise that integrates scientific research, development, design, production, sales, and technical consulting services. The company's annual production of 15000 tons of new materials and water treatment agen... Hunan Hoyoshee Chemical Industrial Co.Ltd was established in 2019, it is a high-tech enterprise that integrates scientific research, development, design, production, sales, and technical consulting services. The company's annual production of 15000 tons of new materials and water treatment agen...
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