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Wenzhou Trustar Machinery Technology Co.,Ltd

  • China,Wenzhou ,Zhejiang
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China Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour
China Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour

  1. China Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour
  2. China Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour
  3. China Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour

Cleanroom-Ready CRS-300 Prefilled Syringe Filling Machine 3600 Pcs/Hour

  1. MOQ: 1 Set
  2. Price: USD 16,000-24,000 / Set
  3. Get Latest Price
Product Contact Material 316L stainless steel, USP Class VI silicone
Machine Weight 780kg
Voltage 220V or 380V, 3 phase, 50/60Hz
Driven Type Servo electric
Payment Terms T/T, L/C at sight
Air Consumption 200 L/min at 0.5 MPa
Applicable Syringe Volume 1-30ml, glass and plastic
Delivery Time 30-40 working days after deposit
Production Capacity 3000-3600 pcs/hour
Filling Needles 4 or 6 needles, peristaltic path
Power 3.5kW
Machine Dimensions L2200 x W1100 x H1750mm
Control System PLC with 7 inch HMI and audit trail
Supply Ability 20 Sets per Month
Warranty 12 months
Filling Accuracy ±1%, in-line checkweigher verified
Format Changeover Time About 15 minutes, tool free
Packaging Details Plywood case with vacuum barrier bag, desiccant and shock sensors
Cleanroom Compatibility ISO Class 5 / Grade A laminar flow
Brand Name TRUSTAR
Model Number CRS-300
Place of Origin Zhejiang, China
Certification CE, ISO 9001:2015

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  1. Product Details
  2. Company Details

Product Specification

Product Contact Material 316L stainless steel, USP Class VI silicone Machine Weight 780kg
Voltage 220V or 380V, 3 phase, 50/60Hz Driven Type Servo electric
Payment Terms T/T, L/C at sight Air Consumption 200 L/min at 0.5 MPa
Applicable Syringe Volume 1-30ml, glass and plastic Delivery Time 30-40 working days after deposit
Production Capacity 3000-3600 pcs/hour Filling Needles 4 or 6 needles, peristaltic path
Power 3.5kW Machine Dimensions L2200 x W1100 x H1750mm
Control System PLC with 7 inch HMI and audit trail Supply Ability 20 Sets per Month
Warranty 12 months Filling Accuracy ±1%, in-line checkweigher verified
Format Changeover Time About 15 minutes, tool free Packaging Details Plywood case with vacuum barrier bag, desiccant and shock sensors
Cleanroom Compatibility ISO Class 5 / Grade A laminar flow Brand Name TRUSTAR
Model Number CRS-300 Place of Origin Zhejiang, China
Certification CE, ISO 9001:2015
High Light CRS-300 prefilled syringe filling machine ,cleanroom-ready syringe filling machine ,3600 pcs/hour syringe filler

The CRS-300 cleanroom-ready prefilled syringe filling machine is engineered for pharmaceutical manufacturers who run multiple product families on a single line and need to switch syringe formats quickly without compromising sterility. Delivered with a stainless steel frame, gap-free welded surfaces and a sloped top cover, it can be wiped down and validated inside an ISO Class 5 cleanroom or Grade A/B filling suite from the first day of installation. Rather than chasing maximum output, the CRS-300 is built around format flexibility, fast line clearance and complete documentation, shortening the time between two production campaigns from days to hours.

Formats are changed using tool-free quick release nest plates, magnetic stopper tooling and a recipe library stored on the machine controller. A complete changeover from a 3 ml standard syringe to a 5 ml barrel, including the line clearance record, is completed in approximately 15 minutes. All product contact parts are 316L stainless steel, borosilicate glass or USP Class VI silicone, and can be removed by hand for autoclaving without tools.

Key Features
  • Sterile by design: the filling zone is a separate Grade A laminar flow tunnel with a 0.3 m per second downflow and a fully welded 316L stainless steel interior, so the machine is supplied ready for cleanroom installation and IQ/OQ documentation.
  • 15 minute format changeover: tool-free quick release nest plates and magnetic stopper tooling allow operators to switch syringe volume, barrel length and cap type within a single shift, keeping a multi-product line productive.
  • Validated line clearance: a built-in clearance checklist guides the operator through every step of the changeover and records the operator ID, timestamp and removed components, producing a printable clearance record for the batch file.
  • Gentle handling of sensitive biologics: a low shear peristaltic filling path with a servo controlled pinch valve minimises foaming and shear stress when handling proteins, vaccines and viscous gels.
  • Integrated weight check: an in-line checkweigher rejects any syringe outside the 1 percent tolerance band and sends the result to the batch report, so fill accuracy is documented rather than assumed.
  • Cleanroom friendly footprint: the compact 2.2 metre frame, recessed cabling and IP65 rated control cabinet reduce cleaning time and allow installation inside an existing barrier system without major civil work.
Technical Specifications
Parameter Specification
ModelCRS-300
Applicable syringe volume1 ml to 30 ml (glass and plastic)
Production capacity3,000 to 3,600 pieces per hour
Filling accuracy±1 percent, verified by in-line checkweigher
Filling needles4 or 6 needles, peristaltic path
Format changeover timeApproximately 15 minutes, tool free
Cleanroom compatibilityISO Class 5 / Grade A laminar flow tunnel
Product contact material316L stainless steel, USP Class VI silicone
Control systemPLC with 7 inch HMI, recipe and audit trail
Air supply0.5 MPa, 200 L per minute, dry and oil free
Power supply220 V or 380 V, three phase, 50/60 Hz, 3.5 kW
Machine dimensionsL 2200 × W 1100 × H 1750 mm
Net weight780 kg
Applications

The CRS-300 suits contract manufacturing organisations that produce small and medium batch sizes across many syringe formats, including hyaluronic acid fillers, saline and heparin flush syringes, vaccine diluents, ophthalmic viscoelastic devices, veterinary injectables and dental anaesthetics. Because the filling path is peristaltic and the format tooling is interchangeable, the same machine can run a 30,000 piece vaccine batch in the morning and a 2,000 piece batch of high value dermal filler in the afternoon without a mechanical rebuild. The downstream interface accepts standard labelling, visual inspection, plunger rod insertion and blister packing modules, and the upstream interface is compatible with nest denesters and tray loaders.

Packaging & Quality Assurance

Before shipment, the CRS-300 is assembled, dry-run tested and then filled with placebo to confirm repeatability across the full speed range. The documentation package includes the IQ/OQ protocol, material certificates for all product contact parts, calibration certificates for the checkweigher and a cleaning validation guide. The machine is shipped in a plywood case with a vacuum barrier bag, desiccant and shock sensors, and lifting points are marked on the frame for cleanroom installation. A twelve month warranty covers mechanical, electrical and control components, and our engineering team provides remote commissioning support together with a spare parts list that keeps critical wear items, silicone tubing and nest plates available for five years.

Company Details

Bronze Gleitlager

,

Bronze Sleeve Bushings

 and 

Graphite Plugged Bushings

 from Quality China Factory
  • Business Type:

    Manufacturer,Exporter

  • Year Established:

    2006

  • Total Annual:

    3000,000-5000,000

  • Employee Number:

    70~100

  • Ecer Certification:

    Verified Supplier

The establishment of TRUSTAR dates back to 2006.During the last 18 years we have acquired expertise and facilities to cater the requirements of our Pharmaceuticals,Food,Cosmetics,Health Care Industries regardsing packaging machinery. We have exported our  machines to Korea, India, Banglad... The establishment of TRUSTAR dates back to 2006.During the last 18 years we have acquired expertise and facilities to cater the requirements of our Pharmaceuticals,Food,Cosmetics,Health Care Industries regardsing packaging machinery. We have exported our  machines to Korea, India, Banglad...

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Get in touch with us

  • Reach Us
  • Wenzhou Trustar Machinery Technology Co.,Ltd
  • Room 3001, Unit 5, Xinhu Mansion, Yuhai Street, Ruian, Wenzhou, Zhejiang, China
  • https://www.mask-makingmachine.com/

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