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Product Name: Linaclotide Acetate / Linaclotide CAS No.: 851199‑59‑2
Molecular Formula: C₅₉H₇₉N₁₅O₂₁S₆
Molecular Weight:1526.84 Grade: Pharmaceutical Grade / API Appearance: White to off‑white lyophilized powder
Linaclotide is a synthetic 14‑amino acid peptide agonist of guanylate cyclase‑C (GC‑C) receptors. It acts locally in the intestinal lumen to increase intestinal fluid secretion and accelerate transit, while reducing visceral hypersensitivity. It is widely used in oral formulations for the treatment of functional gastrointestinal disorders.
Our Linaclotide is manufactured under strict GMP conditions with tight impurity control and full analytical reports, suitable for global pharmaceutical R&D and commercial production.
High purity ≥99.0% by HPLC
Strict control of related substances and diastereomers
Low microbial & endotoxin levels
Full COA, MSDS, NMR, MS, TGA, KF
Stable supply chain & cold-chain shipping
Custom packaging from 1g to bulk
Test Item
Standard
Typical Result
Description
White to off‑white lyophilized powder
Conforms
CAS No.
851199‑59‑2
Conforms
Assay (Peptide Content)
95.0% – 105.0%
99.1%
Purity (HPLC)
≥99.0%
99.5%
Maximum Single Impurity
≤0.5%
0.2%
Total Impurities
≤1.0%
0.6%
Acetic Acid Content
3.0% – 8.0%
5.3%
Water Content (Karl Fischer)
≤5.0%
2.7%
Specific Optical Rotation
−40° to −50°
−45.6°
pH (1% solution)
4.0 – 6.5
5.2
Bacterial Endotoxins
≤5 EU/mg
<2 EU/mg
Microbial Limits
Complies
Complies
Heavy Metals
≤10 ppm
<5 ppm
Residual Solvents
Complies with ICH Q3C
Complies
Storage
2–8°C, sealed, dry, protect from light
Recommended
Shelf Life
24 months
Valid
Main Applications
Irritable Bowel Syndrome with Constipation (IBS‑C)
Chronic Idiopathic Constipation (CIC)
Oral solid dosage formulation development
Preclinical and clinical gastrointestinal research
Pharmaceutical finished dosage R&D
Quality & Compliance
GMP‑compliant production line
EP / USP / in‑house strict standards
Full traceability from raw material to finished product
TSE/BSE free, non‑animal origin
Stable quality for long‑term cooperation
Packaging & Shipping
Inner: Sealed sterile vial with desiccant
Outer: Aluminum foil bag + carton
Shipping: Cold chain (2–8°C) with temperature recorder
Neutral packaging & custom labeling available
Order Information
MOQ: 1g
Lead time: 1–2 weeks (in stock)
Full export documents: COA, MSDS, TDS, GMP
Technical support for formulation development
Company Details
Bronze Gleitlager
,
Bronze Sleeve Bushings
and
Graphite Plugged Bushings
from Quality China Factory
Business Type:
Manufacturer,Distributor/Wholesaler,Exporter
Year Established:
2016
Total Annual:
5000000-6000000
Employee Number:
50~100
Ecer Certification:
Verified Supplier
About Us
Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b...
About Us
Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b...