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GMP factory supply high purity Bremelanotide PT-141 peptide CAS 189691-06-3

China GMP factory supply high purity Bremelanotide PT-141 peptide CAS 189691-06-3

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GMP factory supply high purity Bremelanotide PT-141 peptide CAS 189691-06-3

MOQ： 1g
Price： 220USD
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Test Method	HPLC HNMR
Einecs	189691-06-3
Casnumber	Varies by peptide
Packagingmaterial	PVC bottle or aluminium foil bag
Supply Ability	5kg/month
Packaging Details	PVC bottle or aluminium foil bag
Specification	1g/5g/bag
Color	white
Type	Glp-2
Puritylevel	Pharmaceutical grade
Product Type	Custom Peptide
Payment Terms	L/C,D/A,D/P,T/T,Western Union
Delivery Time	3-7 days
Stocks	Yes
Appearence	Powder
Storage Temp	2-8°C
Lead Time	3-5 working days after payment
Model Number	BVR19
Brand Name	Bovita
Certification	DMF
Place of Origin	Wuhan

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Product Details
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Product Specification


Test Method	HPLC HNMR	Einecs	189691-06-3
Casnumber	Varies by peptide	Packagingmaterial	PVC bottle or aluminium foil bag
Supply Ability	5kg/month	Packaging Details	PVC bottle or aluminium foil bag
Specification	1g/5g/bag	Color	white
Type	Glp-2	Puritylevel	Pharmaceutical grade
Product Type	Custom Peptide	Payment Terms	L/C,D/A,D/P,T/T,Western Union
Delivery Time	3-7 days	Stocks	Yes
Appearence	Powder	Storage Temp	2-8°C
Lead Time	3-5 working days after payment	Model Number	BVR19
Brand Name	Bovita	Certification	DMF
Place of Origin	Wuhan
High Light	GMP Bremelanotide PT-141 peptide powder ，high purity PT-141 research powder ，Bremelanotide PT-141 peptide with warranty

Bremelanotide PT-141 (CAS 189691-06-3) Product Details

Bremelanotide PT-141, with CAS Number 189691-06-3, is a synthetic cyclic heptapeptide and a non-selective melanocortin receptor agonist, also known as Bremelanotide Acetate. It is structurally modified from α-melanocyte stimulating hormone (α-MSH), with N-terminal acetylation, Nle substitution and side-chain lactam cyclization, which significantly enhances its metabolic stability, receptor affinity and biological activity. As a high-purity peptide hormone, it strictly complies with international pharmaceutical standards (GMP, USP, EP) and is widely used in global medical research, clinical trials and pharmaceutical R&D, especially in the fields of dysfunction treatment, melanocortin system research and related development.

Product Basic Information

Item	Details
CAS Number	189691-06-3
Product Name	Bremelanotide; PT-141; Bremelanotide Acetate; Vyleesi® (FDA-approved brand)
Chemical Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	Approx. 1025.18
Appearance	White to Off-White Loose Solid Powder
Purity	≥98% (HPLC); ≥99.5% available for medical grade; Single impurity ≤2%
Solubility	Slightly soluble in DMSO, Methanol and Water (ultrasonic assistance recommended); Soluble in PBS and normal saline; Homogeneous suspension in appropriate buffers
Storage Condition	Sealed, Protected from Light; Powder: -20°C for 2 years, 4°C for 1 year; Dissolved: 4°C for 1 month (bacteriostatic water), -80°C for 6 months; Avoid repeated freeze-thaw cycles and moisture exposure
Shelf Life	24 Months under Proper Storage Conditions (powder)
Peptide Sequence	Ac-Nle-c(Asp-His-D-Phe-Arg-Trp-Lys)-OH (Acetyl-Norleucine-cyclo(Aspartate-Histidine-D-Phenylalanine-Arginine-Tryptophan-Lysine)-Carboxyl)

Pharmacological Action & Clinical Applications

Mechanism of Action

Bremelanotide PT-141 acts as a non-selective agonist of melanocortin receptors (MC1R to MC5R), with particular affinity for MC4R, which plays a key role in the central nervous system's regulation of desire and response. Its cyclic structure, formed by a lactam bridge between the side chain carboxyl of Asp and the side chain amino group of Lys, locks the active conformation and enhances receptor binding affinity. The N-terminal acetylation and Nle substitution (replacing Met) prevent peptide degradation and oxidation, extending its circulating half-life to approximately 2.7 hours. By activating melanocortin receptors in the central nervous system, it regulates desire and response through endogenous pathways, without directly affecting sex hormone levels.

Main Clinical Uses

Dysfunction Research: FDA-approved under the brand name Vyleesi® for the treatment of hypoactive desire disorder (HSDD) in premenopausal women, helping improve desire and response. It is also being studied for potential use in male dysfunction research.
Melanocortin System Research: Widely used as a tool compound to study the physiological functions of the melanocortin system, including pigmentation regulation, energy homeostasis and inflammation modulation.
Pharmaceutical R&D: Serves as a key tool for researching melanocortin receptor pathways and developing new s for dysfunction, obesity and inflammatory diseases, with ongoing clinical trials evaluating its safety and efficacy in different populations.
Animal Model Research: Used in animal experiments to study the role of melanocortin receptors in function, pigmentation and energy metabolism, providing a basis for clinical application research.

Contraindications & Adverse Reactions

Contraindications: Prohibited for patients with hypersensitivity to any component of the product, severe cardiovascular diseases, and those with uncontrolled hypertension or hypotension.

Adverse Reactions: Common reactions may include transient hypotension, flushing, nausea, headache and injection site reactions. Rare reactions include dizziness, fatigue and mild gastrointestinal discomfort. Regular monitoring of blood pressure is recommended during use, especially for patients with cardiovascular disease history. It is not approved for postmenopausal women or men as of March 2026.

Export Compliance & Trade Information

Regulatory Attribute

Bremelanotide PT-141 is classified as a peptide hormone in China, subject to the administration of Import and Export License (Regulatory Code: L). It complies with GMP, USP, EP and other international pharmaceutical standards. It is FDA-approved (brand name Vyleesi®) for HSDD in premenopausal women, but not approved in the EU, UK, Canada or Australia as of March 2026. It is not a DEA-controlled substance, but requires a prescription for clinical use.

HS Code & Declaration Elements

Recommended HS Code: 2937190090 (Other peptide hormones; subject to the latest customs code of the importing country); For finished dosage forms, refer to HS Code 3004 (Medicaments for therapeutic or prophylactic uses). Note that ECCN (Export Control Classification Number) is distinct from HS Code and should be confirmed based on local regulations for US exports.

Declaration Elements: CAS Number, Product Name, Purity, Usage (Medical/Research), Composition, Brand, Peptide Sequence, Structural Modification Information (N-terminal acetylation, cyclization), etc.

Logistics & Packaging

Packaging: Aluminum foil bag or glass vial, labeled with ", Protect from Light, Keep Dry", peptide sequence and structural modification information; sealed packaging to prevent moisture, contamination and peptide degradation. Vacuum-packed options are available upon request. Labeling should comply with FDA requirements for prescription s when exporting to the US market.

Transportation: Ambient temperature shipping is acceptable for short-distance transportation (stable at room temperature for several days during shipping and customs clearance); cold chain transportation (shipping with blue ice) is recommended for long-distance or high-temperature environments to ensure product quality. Avoid extreme temperature changes and repeated freeze-thaw cycles.

Quality Assurance & After-Sales Service

Strict Quality Control: Each batch of products undergoes HPLC, MS and peptide sequence verification tests to ensure purity, stability and structural accuracy; endotoxin testing (≤50EU/mg) and amino acid composition analysis (≤±10%) are available upon request. Peptide content ≥80.0% is guaranteed for research and medical grade products.
Customized Service: We can provide customized packaging and specifications according to customer needs, including small-volume research-grade products (≥99% purity) and large-volume medical-grade products, as well as customized solvent formulation guidance for in vivo and in vitro use.

Company Details

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Business Type:

Manufacturer,Distributor/Wholesaler,Exporter 
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Year Established:

2016 
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Total Annual:

5000000-6000000
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Employee Number:

50~100 
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About Us Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b... About Us Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b...

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