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Beijing Bovita Biomed Co.,Ltd.

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China GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0
China GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0

  1. China GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0
  2. China GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0

GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0

  1. MOQ: 5g
  2. Price: 200USD/G
  3. Get Latest Price
purity 99%
Color White
Appearance Powder
Payment Terms D/A,L/C,D/P,T/T,Western Union
Supply Ability 5kg/month
Stocks Avaliable
Name Difelikefalin
Packaging Details aluminium foil bag
Delivery time 3-5 days
Brand Name Bovita
Certification DMF
Place of Origin SICHUAN
Model Number BVP010

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Product Specification

purity 99% Color White
Appearance Powder Payment Terms D/A,L/C,D/P,T/T,Western Union
Supply Ability 5kg/month Stocks Avaliable
Name Difelikefalin Packaging Details aluminium foil bag
Delivery time 3-5 days Brand Name Bovita
Certification DMF Place of Origin SICHUAN
Model Number BVP010
High Light GMP Difelikefalin peptide powderHigh purity Difelikefalin powderDifelikefalin peptide with DMF

GMP factory sale High Purity Difelikefalin peptide powder cas 1024828-77-0 Difelikefalin peptide with DMF

Difelikefalin peptide powder, CAS 1024828-77-0, high-purity CR845, research-grade KOR agonist, difelikefalin for pruritus research, peripheral opioid peptide, lyophilized difelikefalin

Difelikefalin (CAS 1024828-77-0), also known as CR845, FE-202845, and Korsuva™, is a synthetic, peripherally selective κ-opioid receptor (KOR) agonist. It acts by binding to peripheral KORs to modulate pruritus, inflammatory signals, and without significant central nervous system penetration, avoiding central adverse effects like respiratory depression. This tetrapeptide is a key research tool for studying itch mechanisms, neuro-immune interactions, and analgesic development.

Parameter Specification
Chemical Name Difelikefalin (Free Base)
CAS Number 1024828-77-0
Molecular Formula C₃₆H₅₃N₇O₆
Molecular Weight ~679.85 g/mol
Purity ≥98.0% (HPLC), with single impurity ≤1.0%
Appearance White to off-white lyophilized powder
Solubility Water ≥100 mg/mL; DMSO ≥90 mg/mL
Storage -20°C, sealed, dry, protected from light
Shelf Life 2 years at -20°C; 1 year at -20°C (open); 6 months/-1 month in solvent at -80°C/-20°C

Key Features & Advantages


  • Peripheral Selectivity: Limited blood-brain barrier penetration minimizes central side effects.
  • High Potency & Selectivity: Targets KORs with minimal cross-reactivity to other opioid receptors.
  • Rigorous QC: HPLC, LC-MS, and NMR confirmation for batch consistency.
  • Low Endotoxin: ≤1000 EU/mg (standard for research-grade peptides).
  • Flexible Packaging: Available in mg to g scales with custom vial options.

Research Applications


  • Pruritus Research: Investigating uremic pruritus in hemodialysis patients and chronic itch mechanisms.
  • & Inflammation: Studying peripheral analgesia and anti-inflammatory pathways in post-op and chronic models.
  • Neuro-Immunology: Exploring KOR-mediated immune cell modulation and neuroinflammation.
  • Pharmaceutical R&D: Reference standard for formulation, bioactivity, and safety profiling.
  • Neuroscience: Analyzing peripheral opioid signaling and sensory neuron function.

Quality Control & Documentation


Each batch includes:

  • HPLC purity & identity verification
  • LC-MS molecular confirmation
  • ¹H-NMR structural consistency
  • Endotoxin, heavy metal, and microbial limits testing
  • Full COA, SDS, and batch traceability (available on request)

Handling & Storage


  • For Research Use Only. Not for human/veterinary clinical use.
  • Store lyophilized powder at -20°C upon receipt; aliquot to avoid freeze-thaw cycles.
  • Ship ambient for short durations; maintain cold chain for long-term transport.

Synonyms


CR845, FE-202845, Korsuva™, D-Phe-D-Phe-D-Leu-D-Lys-[γ-(4-N-piperidinyl)amino carboxylic acid]

Shipping & Logistics


  • Global express delivery with temperature-controlled packaging.
  • In-stock orders ship within 24–48 hours; discreet, secure packaging for customs compliance.

Compliance


Manufactured in ISO 9001/13485-certified facilities to meet global research standards.

Company Details

Bronze Gleitlager

,

Bronze Sleeve Bushings

 and 

Graphite Plugged Bushings

 from Quality China Factory
  • Business Type:

    Manufacturer,Distributor/Wholesaler,Exporter

  • Year Established:

    2016

  • Total Annual:

    5000000-6000000

  • Employee Number:

    50~100

  • Ecer Certification:

    Verified Supplier

About Us Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b... About Us Founded in Fangshan District, Beijing, Bovita is a forward-thinking biotech startup specializing in high-purity peptide products and premium dietary supplement raw materials. Rooted in the rigorous standards of China’s pharmaceutical and chemical industry, we are dedicated to b...

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Get in touch with us

  • Reach Us
  • Beijing Bovita Biomed Co.,Ltd.
  • Floor 4th No.62 of Shan Shui Huihao Gardan, Dou Dian Town,Fangshan District, Beijing,China . Zip 102402
  • https://www.bovitabio.com/

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