Customizable THROBIO CaHA Calcium Hydroxylapatite Dermal Filler Raw Materials

• Product Description: Medical-grade CaHA (Calcium Hydroxylapatite) is a premium inorganic mineral regenerative dermal filler, chemically identical to the natural mineral components of human bones and teeth. It is formulated with uniform high-purity CaHA microspheres suspended in a biocompatible CMC gel carrier, forming a dual-phase composite filling system. Different from polymer-based fillers, CaHA features rigid bony support and powerful collagen stimulation capability, delivering immediate volumizing contouring and long-term dermal regeneration. Widely recognized in global aesthetic medicine, it is ideal for deep facial volume restoration, sagging lifting, severe wrinkle improvement and bony contour sculpting, achieving firm, three-dimensional and long-lasting facial rejuvenation effects.
• Product Features: CaHA possesses outstanding rigid supporting performance superior to HA and lactic acid-based fillers, with strong anti-deformation ability for stable bony contour shaping. It adopts pure synthetic mineral ingredients with zero animal-derived components, excellent biocompatibility and ultra-low immune rejection risk, ensuring high clinical safety. Featuring a unique immune tolerance particle size window, the uniform microspheres avoid excessive phagocytosis and granuloma formation, with mild inflammatory response and stable tissue compatibility. It combines instant gel filling and long-term microsphere regeneration, with a balanced degradation cycle and no sudden volume loss. It effectively stimulates the synchronous regeneration of type I and type III collagen as well as elastic fibers, realizing firm skin tightening and durable anti-aging effects without rigid or unnatural facial expressions.
• Technical Principle: CaHA relies on bionic mineral structure and biological stimulation mechanism to achieve dual aesthetic effects. After subcutaneous injection, the CMC gel carrier provides immediate filling and volumizing effect to quickly repair facial hollowing and wrinkles. The uniformly sized CaHA microspheres stay stably in the deep dermis and subdermal tissue, which cannot be completely phagocytosed by macrophages, forming a mild and stable tissue microenvironment. It regulates the transformation of inflammatory factors from M1 to M2, continuously activating dermal fibroblasts, promoting the proliferation of autologous collagen, elastic fibers and angiogenesis. With the gradual degradation of the gel carrier and slow metabolism of CaHA microspheres, the newly generated autologous soft tissue replaces the filler, forming natural, firm and long-lasting three-dimensional facial contours.
• Production Process: Medical-grade CaHA adopts ultra-pure mineral synthesis and precision microsphere molding technology, fully produced in Class 100 dust-free sterile constant-temperature workshop. High-purity calcium and phosphate raw materials are used for hydrothermal synthesis and crystal growth to form regular spherical CaHA crystals. Through multi-stage high-temperature purification, impurity removal and surface modification treatment, trace impurities and invalid crystals are completely eliminated to ensure high purity and uniform sphericity. Precise particle size classification and screening are carried out to lock the optimal microsphere diameter range. Finally, sterile CMC gel homogenization, proportional blending and vacuum sealing packaging are completed, ensuring excellent injection fluidity, stable batch consistency and clinical safety.

Core Technical Parameters