Product Specification

Integrated Anti-Leak Ampoule Washing, Filling, and Sealing Line

High-Speed Automation with Oxyhydrogen Hermetic Sealing for Bioactive Liquids

Product Overview

In the processing of highly sensitive Life sciences formulations, securing an absolute, leak-proof hermetic seal is the ultimate engineering challenge. The Lingyao Integrated Ampoule Filling and Sealing Line is a comprehensive, cGMP-compliant automation ecosystem designed for 1ml to 20ml borosilicate glass ampoules.

Combining ultrasonic washing, hot-air tunnel sterilization, precise liquid dosing, and advanced oxyhydrogen sealing, this unified system achieves a massive output of up to 34,000 ampoules per hour. It represents the definitive solution for high-volume facilities demanding zero micro-leaks, exceptional clarity, and absolute batch integrity.

The Cause: Micro-Leaks and Glass Fractures at High Speeds

When ampoule production scales past 20,000 BPH, traditional manufacturing lines expose critical weaknesses. The most severe issue is micro-leaking caused by unstable sealing flames. Legacy natural gas torches often fluctuate, leaving microscopic pinholes or causing the glass tip to crack as it cools. This ruins expensive Healthcare solutions and leads to devastating batch recalls.

Furthermore, moving fragile glass ampoules through separate washing, sterilizing, and filling machines creates mechanical stress. Aggressive star-wheels and misaligned transfers cause glass-to-glass friction, driving breakage rates to unacceptable levels and contaminating the sterile processing environment.

The Solution: Oxyhydrogen Fusion and Synchronized Transport

The Lingyao engineering team resolved the micro-leak crisis by integrating an Advanced Oxyhydrogen Sealing System. By mixing liquefied gas with oxygen or utilizing an integrated oxyhydrogen generator, the system produces an intensely focused, perfectly clean flame. This instantly melts and draws the borosilicate glass, fusing it into a flawless, carbon-free dome that guarantees zero leakage.

To eliminate glass breakage, the entire line—from the ultrasonic washing station through the 350°C depyrogenation tunnel to the filling core—is electronically synchronized. Operating under an Advanced Intelligent Electronic Control Technology framework, the smooth, servo-driven transport mechanism drastically reduces mechanical impact, achieving an industry-leading breakage rate of ≤ 0.1%.

Specifications

Application Scenarios

• Advanced Life Sciences: High-speed, secure packaging for critical Bioactive liquids requiring absolute zero-contamination barrier protection.

• Specialized Healthcare Solutions: Leak-proof filling for concentrated therapeutic solutions and temperature-sensitive suspensions.

• Premium Cosmeceuticals: Pristine, carbon-free sealing for high-value aesthetic serums and pure antioxidant formulations.

How It Works

Empty ampoules are loaded and subjected to intense ultrasonic cavitation and alternating water/air flushes, ensuring >99.9% clarity. They automatically advance through the laminar-flow hot air circulation oven, where they are thoroughly depyrogenated and cooled under ISO Class 5 conditions.

Inside the filling core, the ampoules are precision-dosed. An optional nitrogen purging system displaces oxygen inside the ampoule neck to protect the formulation. Immediately following the fill, the oxyhydrogen sealing station applies its precise flame. The sealed ampoules are then cooled and safely discharged for secondary packaging.

Comprehensive Global Integration

Deploying a complete ampoule line requires flawless execution and localized expertise. Leveraging our highly advanced TachoCraft Thailand manufacturing base, we provide equipment that is engineered to withstand diverse global climates.

We offer full Accompanying Production Services, including pre-shipment FAT (Factory Acceptance Testing), site installation, and hands-on operator training. Our engineering team provides meticulous IQ/OQ/PQ validation dossiers, ensuring your new line swiftly passes rigorous SABER/SASO inspections in Saudi Arabia and meets compliance standards across emerging African markets. We look forward to discussing your turnkey layout at the upcoming 2026 regional healthcare exhibitions.